Definition: Enaesthesia, a condition characterized by pain that cannot be relieved with analgesics or sedatives, is described as 'acnese'. This term encompasses conditions where the body loses its ability to regulate the sensation caused by pain. The cause of acenosis can vary and ranges from general physiological problems (such as diabetes mellitus) to neurological disorders. Acenosis has a wide range of clinical manifestations, including: 1.

Tachycardia:

Rapid heart rate that is excessive in response to external stimuli. 2.

Dehydration:

Loss of fluid due to decreased blood volume and body fluids (most commonly water). 3.

Dizziness or fainting:

Loss of balance or coordination due to internal organs being unresponsive to pain signals. 4.

Tremors and spasms:

Involuntary muscle movements that can cause discomfort, especially if the muscles are not stimulated. 5.

Chills, shivers, or hypothermia:

Loss of body heat because of lack of cooling through circulation. The exact mechanism by which acenosis occurs is not fully understood but is thought to involve an inability of the brain to sense and control pain signals. This condition can have devastating effects on individuals who experience it as it can lead to severe symptoms that may include convulsions, coma, or death.

acenesthesia