Definition: The word "adipokine" stands for adiponectin, which has many roles in the body: it can lower blood sugar levels, reduce inflammation, boost immune function, and regulate metabolic processes. Adipokines are released by fat cells that act as messengers to other organs. They can be produced by adipocytes or activated by insulin, lipase, or other hormones. They interact with receptors on cell membrane-bound proteins that facilitate their transport across the cell membrane. Adipokines include:
Adiponectin: This is an adipocyte-specific hormone and its function is to lower blood sugar levels.
Insulin-like growth factor-1 (IGF-1): This is a growth factor, which stimulates cells and tissues in response to insulin, including fat cells.
Insulin-like growth factor-2 (IGF-2): This is another growth factor, also associated with the function of fat cells.
Metabolic agonist (MAG)-like ligand 1/3 (MGL1/MGL3): This is a hormone that stimulates the activity of gut bacteria, which can stimulate and regulate the metabolism of fat. Adipokines can have both beneficial and harmful effects on the body's response to insulin. On one hand, they can help control blood sugar levels by lowering glucose uptake in adipocytes. However, too much IGF-1 can lead to weight gain and other health issues. In summary, Adipopexia is a state of imbalance in the production and release of adipokines in the body. It may indicate various disorders such as diabetes, obesity, or inflammatory conditions.

adipopexia