Definition: In the King James Version (KJV), "adrenocorticotrophic" refers to a type of tumor that is associated with adrenocortical disorders, such as Addison's disease and Cushing's syndrome. This condition is characterized by abnormal levels of cortisol in the body, which can lead to symptoms like fatigue, weight loss, and elevated blood pressure. The term "adrenocorticotrophic" comes from the Latin words for "adrenal," meaning adrenal gland, and "corticotropic hormone," which is also a hormone produced by the adrenal gland. The adrenocorticotropin (AD) is an endocrine hormone that regulates the function of the adrenal glands. In summary, "adrenocorticotrophic" is referring to conditions involving abnormal levels of cortisol in the body due to Addison's disease or Cushing's syndrome. These disorders often involve increased production and release of AD by the adrenal gland, leading to various symptoms like weight loss, fatigue, and high blood pressure.
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