Definition: The term "Meningococcal Conjugate Vaccine" refers to a vaccine that specifically targets the meningococcal group B, group C, or group E strains in addition to the group A (A1) or group C (C1) strain. The meningococcal group B and group C strains are commonly found in the human brain and spinal cord and have been responsible for outbreaks of meningitis and encephalitis. The meningococcal Conjugate Vaccine is designed to neutralize the active component, the beta 2-microsomal proteins that are normally found in meningococci. This helps prevent an infection with a bacterial or viral type from spreading into a person's bloodstream. The vaccine can also help protect against strains of pneumococcus, which affects many other parts of the body. The conjugate vaccine is not intended for prophylaxis and should only be administered if a patient has been infected with meningococcal bacteria. It must be given in combination with the standard meningococcal (A1, C1) or group B (V) strain vaccines to provide complete protection against all three strains. The specific dose of the conjugate vaccine varies depending on the type of meningococcal vaccine being used and is usually recommended for a full vaccination regimen. It is important to note that the efficacy of the conjugate vaccine against meningococcal disease can vary depending on various factors such as individual immunity, vaccination history, and the specific strains encountered in a particular population. Overall, the meningococcal Conjugate Vaccine helps protect against meningococcal disease and is an important tool for public health to prevent outbreaks.
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