Definition: Acetylization, also known as acetylcholinesterase (ACHE) or choline ester transamination, refers to a specific enzymatic process by which neurotransmitters such as dopamine and serotonin are converted from a choline moiety (CH3O-CH2NH) to its respective ester (CH3O-CH(OH)N). This conversion is essential for the normal functioning of nerve cells and is an important cellular energy exchange pathway. The detailed definition of acetylcholinesterase enzyme: Acetylcholinesterase is a catalytic enzyme that inactivates the acetyl group of choline. The acetyl group (CH3O-CH2NH) acts as an acceptor, binding to the amino group of the neurotransmitter molecule and allowing the conversion from choline to its ester form (CH3O-CH(OH)N). This process is crucial for maintaining the normal function of nerve cells. The enzyme is typically found in the cerebellum and other areas of the brain where neurotransmitters are released, but it's also present in muscles, glands, and other tissues that secrete acetylcholine. Acetylcholinesterase plays a dual role in neuronal function: It facilitates the transport of neurotransmitters between neurons and vesicles to other cells. It is involved in the formation of excitatory synaptic vesicle complexes (E-SVs) that play important roles in transmitting impulses, regulating action potentials, and triggering synaptogenesis.

acetylized